|Strain Name||C57BL/6N-Garptm1(GARP)TGFB1tm1(TGFB1)/Bcgen||Common Name||B-hGARP/hTGFB1 mice|
Protein expression analysis in blood
Strain specific TGFB1 expression analysis in wild-type C57BL/6 mice and homozygous B-hGARP/hTGFB1 mice by flow cytometry. Blood were isolated from wild-type C57BL/6 mice and homozygous B-hGARP/hTGFB1 mice. Mouse TGFB1 was detectable in wild-type mice. Human TGFB1 was only detectable in homozygous B-hGARP/hTGFB1 mice.
Analysis of leukocytes cell subpopulation in spleen
Combination therapy of anti-mouse PD-1 antibody and anti-human GARP/latent-TGFβ1 antibody