Strain Name |
C57BL/6N-Luca2tm1(LUCA2)Bcgen/Bcgen
|
Common Name | B-hLUCA2 mice |
Background | C57BL/6N | Catalog number |
112499 |
Aliases |
Human: HYAL2 |
Description
Mechanism of action
Gene targeting strategy for B-hLUCA2 mice.
The exons 2~4 of mouse Luca2 gene that encode the full-length protein were replaced by human LUCA2 exons 2~4 in B-hLUCA2 mice.
Model validation
mRNA expression analysis
Summary
Protein expression analysis:
LUCA2 protein was detected in stomach, testis, lung, spleen, liver and skeletal muscle of wild-type C57BL/6 mice and homozygous B-hLUCA2 mice.